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Lung Type 2 innate lymphoid cells express CysLT1R that regulates Th2 cytokine production
BACKGROUND: Cysteinyl leukotrienes contribute to asthma pathogenesis, in part through CysLT1 receptor (CysLT1R). Recently discovered lineage-negative type 2 innate lymphoid cells (ILC2) potently produce IL-5 and IL-13. OBJECTIVES: We hypothesized that lung ILC2 may be activated by leukotrienes throu...
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| Main Authors: | , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2013
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3704056/ https://ncbi.nlm.nih.gov/pubmed/23688412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2013.03.048 |
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