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Reversion of a fungal genetic code alteration links proteome instability with genomic and phenotypic diversification
Many fungi restructured their proteomes through incorporation of serine (Ser) at thousands of protein sites coded by the leucine (Leu) CUG codon. How these fungi survived this potentially lethal genetic code alteration and its relevance for their biology are not understood. Interestingly, the human...
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Główni autorzy: | , , , , , , , , , , , , , , , |
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Format: | Artigo |
Język: | Inglês |
Wydane: |
National Academy of Sciences
2013
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3704024/ https://ncbi.nlm.nih.gov/pubmed/23776239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1302094110 |
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