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Activation and dynamic network of the M2 muscarinic receptor

G-protein-coupled receptors (GPCRs) mediate cellular responses to various hormones and neurotransmitters and are important targets for treating a wide spectrum of diseases. Although significant advances have been made in structural studies of GPCRs, details of their activation mechanism remain uncle...

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Detalhes bibliográficos
Main Authors: Miao, Yinglong, Nichols, Sara E., Gasper, Paul M., Metzger, Vincent T., McCammon, J. Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703993/
https://ncbi.nlm.nih.gov/pubmed/23781107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1309755110
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