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Single-Molecule Studies of the Lysine Riboswitch Reveal Effector Dependent Conformational Dynamics of the Aptamer Domain

The lysine riboswitch is a cis-acting RNA genetic regulatory element found in the leader sequence of bacterial mRNAs coding for proteins related to biosynthesis or transport of lysine. Structural analysis of the lysine-binding aptamer domain of this RNA has revealed that it completely encapsulates t...

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Detalhes bibliográficos
Main Authors: Fiegland, Larry R., Garst, Andrew D., Batey, Robert T., Nesbitt, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703957/
https://ncbi.nlm.nih.gov/pubmed/23067368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3007753
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