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The Yersinia virulence effector YopM binds caspase-1 to arrest inflammasome assembly and processing
Inflammasome assembly activates caspase-1 and initiates the inflammatory cell death program pyroptosis, which is protective against numerous pathogens. Consequently, several pathogens, including the plague causing bacterium Yersinia pestis, avoid activating this pathway to enhance their virulence. H...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3703949/ https://ncbi.nlm.nih.gov/pubmed/23245324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2012.10.020 |
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