Altered Sleep Regulation in a Mouse Model of SCN1A-Derived Genetic Epilepsy with Febrile Seizures Plus (GEFS+)

PURPOSE: Mutations in the voltage-gated sodium channel SCN1A are responsible for a number of epilepsy disorders, including genetic epilepsy with febrile seizures plus (GEFS+) and Dravet syndrome. In addition to seizures, patients with SCN1A mutations often experience sleep abnormalities, suggesting...

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Hauptverfasser: Papale, Ligia A., Makinson, Christopher D., Ehlen, J. Christopher, Tufik, Sergio, Decker, Michael J., Paul, Ketema N., Escayg, Andrew
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703918/
https://ncbi.nlm.nih.gov/pubmed/23311867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.12060
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