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Opposing roles of STAT4 and Dnmt3a in Th1 gene regulation
The Signal Transducer and Activator of Transcription factor STAT4 is a critical regulator of Th1 differentiation and inflammatory disease. Yet, how STAT4 regulates gene expression is still unclear. In this report, we define a STAT4-dependent sequence of events including H3K4 methylation, Jmjd3 assoc...
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| Main Authors: | , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3703830/ https://ncbi.nlm.nih.gov/pubmed/23772023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1203229 |
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