MMP-3 Contributes to Nigrostriatal Dopaminergic Neuronal Loss, BBB Damage, and Neuroinflammation in an MPTP Mouse Model of Parkinson's Disease

The present study examined whether matrix metalloproteinase-3 (MMP-3) participates in the loss of dopaminergic (DA) neurons in the nigrostriatal pathway in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease with blood brain barrier (BBB) damage and infiltra...

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Autori principali: Chung, Young Cheul, Kim, Yoon-Seong, Bok, Eugene, Yune, Tae Young, Maeng, Sungho, Jin, Byung Kwan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703803/
https://ncbi.nlm.nih.gov/pubmed/23853428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/370526
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