Paeoniflorin attenuates neuroinflammation and dopaminergic neurodegeneration in the MPTP model of Parkinson's disease by activation of adenosine A(1) receptor

1. This study examined whether Paeoniflorin (PF), the major active components of Chinese herb Paeoniae alba Radix, has neuroprotective effect in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease (PD). 2. Subcutaneous administration of PF (2.5 and 5 mg kg...

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Bibliographische Detailangaben
Hauptverfasser: Liu, Hua-Qing, Zhang, Wei-Yu, Luo, Xue-Ting, Ye, Yang, Zhu, Xing-Zu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2006
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Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751566/
https://ncbi.nlm.nih.gov/pubmed/16582933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706732
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