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Extrachromosomal microDNAs and chromosomal microdeletions in normal tissues

We have identified tens of thousands of short extrachromosomal circular DNAs (microDNA) in mouse tissues as well as mouse and human cell lines. These microDNAs are 200–400 bp long, derived from unique non-repetitive sequence and are enriched in the 5' untranslated regions of genes, exons and Cp...

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Detalhes bibliográficos
Main Authors: Shibata, Yoshiyuki, Kumar, Pankaj, Layer, Ryan, Willcox, Smaranda, Gagan, Jeffrey R., Griffith, Jack D., Dutta, Anindya
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703515/
https://ncbi.nlm.nih.gov/pubmed/22403181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1213307
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