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Extrachromosomal microDNAs and chromosomal microdeletions in normal tissues

We have identified tens of thousands of short extrachromosomal circular DNAs (microDNA) in mouse tissues as well as mouse and human cell lines. These microDNAs are 200–400 bp long, derived from unique non-repetitive sequence and are enriched in the 5' untranslated regions of genes, exons and Cp...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Shibata, Yoshiyuki, Kumar, Pankaj, Layer, Ryan, Willcox, Smaranda, Gagan, Jeffrey R., Griffith, Jack D., Dutta, Anindya
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703515/
https://ncbi.nlm.nih.gov/pubmed/22403181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1213307
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