A repressor protein, Mnt, is a novel negative regulator of vascular smooth muscle cell hypertrophy by angiotensin II and neointimal hyperplasia by arterial injury

OBJECTIVE: The Max-interacting protein Mnt is a transcriptional repressor that can antagonize the transcriptional and proliferation-related activities of Myc. Here, we tested the hypothesis that Mnt is a negative regulator of pathological vascular remodeling. METHODS: Adenovirus encoding Mnt or cont...

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Main Authors: Takayanagi, Takehiko, Eguchi, Akito, Takaguri, Akira, Hinoki, Akinari, Bourne, Allison M., Elliott, Katherine J, Hurlin, Peter J., Eguchi, Satoru
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703465/
https://ncbi.nlm.nih.gov/pubmed/23535568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2013.02.033
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