A Phase I clinical trial of the combination of imatinib and paclitaxel in patients with advanced or metastatic solid tumors refractory to standard therapy

PURPOSE: Pre-clinical data suggest that combining imatinib with traditional cytotoxic chemotherapy may improve imatinib efficacy. We conducted a Phase I study of imatinib in combination with paclitaxel in patients with advanced or metastatic solid tumors. METHODS: Patients were accrued to the study...

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Detalhes bibliográficos
Main Authors: Pishvaian, Michael J., Slack, Rebecca, Koh, Eunice Y., Beumer, Jan H., Hartley, Marion L., Cotarla, Ion, Deeken, John, He, Aiwu Ruth, Hwang, Jimmy, Malik, Shakun, Firozvi, Kashif, Liu, Minetta, Elston, Beth, Strychor, Sandy, Egorin, Merrill J., Marshall, John L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703247/
https://ncbi.nlm.nih.gov/pubmed/23014737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-012-1969-9
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