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Effect of antacid on imatinib absorption
PURPOSE: Imatinib often causes gastric upset resulting in frequent co-administration of an antacid. Elevated gastric pH, delayed gastric emptying, or introduction of Mg(2+)/Al(3+) could potentially change imatinib absorption, thereby affecting the therapeutic effectiveness of imatinib. Indeed, antac...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2715160/ https://ncbi.nlm.nih.gov/pubmed/18500518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-008-0778-7 |
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