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Comparison of Iodothyronine 5′-Deiodinase and Other Thyroid-Hormone-dependent Enzyme Activities in the Cerebral Cortex of Hypothyroid Neonatal Rat: EVIDENCE FOR ADAPTATION TO HYPOTHYROIDISM

Recent studies have shown that ∼75% of the nuclear 3,5,3′-triiodothyronine (T(3)) present in adult rat cerebral cortex (Cx) derives from 5′-deiodination of thyroxine (T(4)) within this tissue. The activity of iodothyronine 5′-deiodinase (I 5′D), the enzyme catalyzing T(4) to T(3) conversion, increas...

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Detalhes bibliográficos
Main Authors: Silva, J. Enrique, Larsen, P. Reed
Formato: Artigo
Idioma:Inglês
Publicado em: 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC370324/
https://ncbi.nlm.nih.gov/pubmed/6215429
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