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Comparison of Iodothyronine 5′-Deiodinase and Other Thyroid-Hormone-dependent Enzyme Activities in the Cerebral Cortex of Hypothyroid Neonatal Rat

Recent studies have shown that ∼75% of the nuclear 3,5,3′-triiodothyronine (T(3)) present in adult rat cerebral cortex (Cx) derives from 5′-deiodination of thyroxine (T(4)) within this tissue. The activity of iodothyronine 5′-deiodinase (I 5′D), the enzyme catalyzing T(4) to T(3) conversion, increas...

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Vydáno v:J Clin Invest
Hlavní autoři: Silva, J. Enrique, Larsen, P. Reed
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 1982
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370324/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6215429/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110699
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