Comparison of Iodothyronine 5′-Deiodinase and Other Thyroid-Hormone-dependent Enzyme Activities in the Cerebral Cortex of Hypothyroid Neonatal Rat
Recent studies have shown that ∼75% of the nuclear 3,5,3′-triiodothyronine (T(3)) present in adult rat cerebral cortex (Cx) derives from 5′-deiodination of thyroxine (T(4)) within this tissue. The activity of iodothyronine 5′-deiodinase (I 5′D), the enzyme catalyzing T(4) to T(3) conversion, increas...
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| Veröffentlicht in: | J Clin Invest |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
1982
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370324/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6215429/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110699 |
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