Identifying and Targeting ROS1 Gene Fusions in Non-Small Cell Lung Cancer

PURPOSE: Oncogenic gene fusions involving the 3’ region of ROS1 kinase have been identified in various human cancers. In this study, we sought to characterize ROS1 fusion genes in non-small cell lung cancer (NSCLC) and establish the fusion proteins as drug targets. EXPERIMENTAL DESIGN: A NSCLC tissu...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Davies, Kurtis D., Le, Anh T., Theodoro, Mariana F., Skokan, Margaret C., Aisner, Dara L., Berge, Eamon M., Terracciano, Luigi M., Incarbone, Matteo, Roncalli, Massimo, Cappuzzo, Federico, Camidge, D. Ross, Varella-Garcia, Marileila, Doebele, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703205/
https://ncbi.nlm.nih.gov/pubmed/22919003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-0550
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares