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Treatment of Lactic Acidosis with Dichloroacetate in Dogs

Lactic acidosis is a clinical condition due to accumulation of H(+) ions from lactic acid, characterized by blood lactate levels >5 mM and arterial pH <7.25. In addition to supportive care, treatment usually consists of intravenous NaHCO(3), with a resultant mortality >60%. Dichloroacetate...

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Bibliographic Details
Main Authors: Park, Robert, Arieff, Allen I., Leach, William, Lazarowitz, Virginia C.
Format: Artigo
Language:Inglês
Published: 1982
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC370294/
https://ncbi.nlm.nih.gov/pubmed/6288773
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