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T Cell Activation Threshold Regulated by E3 Ubiquitin Ligase Cbl-b Determines Fate of Inducible Regulatory T Cells
E3 ubiquitin ligase Cbl-b is critical for establishing the threshold for T cell activation, and is essential for induction of T cell anergy. Recent studies suggest that Cbl-b is involved in the development of inducible CD4(+)CD25(+) regulatory T cells (iTregs). In this study, we report that the opti...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3702637/ https://ncbi.nlm.nih.gov/pubmed/23749633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202068 |
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