Profiling of normal and malignant breast tissue show CD44(high)/CD24(low) phenotype as a predominant stem/progenitor marker when used in combination with Ep-CAM/CD49f markers

BACKGROUND: Accumulating evidence supports cancer to initiate and develop from a small population of stem-like cells termed as cancer stem cells (CSC). The exact phenotype of CSC and their counterparts in normal mammary gland is not well characterized. In this study our aim was to evaluate the pheno...

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Detaylı Bibliyografya
Asıl Yazarlar: Ghebeh, Hazem, Sleiman, Ghida Majed, Manogaran, Pulicat S, Al-Mazrou, Amer, Barhoush, Eman, Al-Mohanna, Falah H, Tulbah, Asma, Al-Faqeeh, Khalid, Adra, Chaker N
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3702414/
https://ncbi.nlm.nih.gov/pubmed/23768049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-289
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