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FOXP3(+ )T(regs )and B7-H1(+)/PD-1(+ )T lymphocytes co-infiltrate the tumor tissues of high-risk breast cancer patients: Implication for immunotherapy
BACKGROUND: Recent studies have demonstrated a direct involvement of B7-H1, PD-1 and FOXP3 molecules in the immune escape of cancer. B7-H1 is an inhibitory molecule that binds to PD-1 on T lymphocytes, while FOXP3 is a marker for regulatory T cells (T(regs)). We have previously demonstrated the asso...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2279136/ https://ncbi.nlm.nih.gov/pubmed/18294387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-57 |
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