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Is there in vivo evidence for amino acid shuttles carrying ammonia from neurons to astrocytes?

The high in vivo flux of the glutamate/glutamine cycle puts a strong demand on the return of ammonia released by phosphate activated glutaminase from the neurons to the astrocytes in order to maintain nitrogen balance. In this paper we review several amino acid shuttles that have been proposed for b...

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Detalhes bibliográficos
Main Authors: Rothman, Douglas L., De Feyter, Henk M., Maciejewski, Paul K., Behar, Kevin L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3702378/
https://ncbi.nlm.nih.gov/pubmed/23104556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-012-0898-7
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