A novel radioprotective function for the mitochondrial tumor suppressor protein Fus1

FUS1/TUSC2 is a mitochondrial tumor suppressor with activity to regulate cellular oxidative stress by maintaining balanced ROS production and mitochondrial homeostasis. Fus1 expression is inhibited by ROS, suggesting that individuals with a high level of ROS may have lower Fus1 in normal tissues and...

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Autores principales: Yazlovitskaya, E M, Uzhachenko, R, Voziyan, P A, Yarbrough, W G, Ivanova, A V
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2013
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3702292/
https://ncbi.nlm.nih.gov/pubmed/23788044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.212
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