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A novel radioprotective function for the mitochondrial tumor suppressor protein Fus1
FUS1/TUSC2 is a mitochondrial tumor suppressor with activity to regulate cellular oxidative stress by maintaining balanced ROS production and mitochondrial homeostasis. Fus1 expression is inhibited by ROS, suggesting that individuals with a high level of ROS may have lower Fus1 in normal tissues and...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3702292/ https://ncbi.nlm.nih.gov/pubmed/23788044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.212 |
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