Organopalladium compound 7b targets mitochondrial thiols and induces caspase-dependent apoptosis in human myeloid leukemia cells

The advances in the treatment of chronic myeloid leukemia (CML) during the last years were also accompanied by the development of evading strategies by tumor cells, resulting in chemotherapy resistance in some patients. Patented organopalladium compounds derived from the reaction of N,N-dimethyl-1-p...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Moraes, V W R, Caires, A C F, Paredes-Gamero, E J, Rodrigues, T
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3702286/
https://ncbi.nlm.nih.gov/pubmed/23744358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.190
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky