TIMP-2 modulates cancer cell transcriptional profile and enhances E-cadherin/beta-catenin complex expression in A549 lung cancer cells

Tissue Inhibitor of Metalloproteinase 2 (TIMP-2) plays an essential role in regulating matrix remodeling, cell growth, differentiation, angiogenesis and apoptosis in vitro and in vivo. We have recently shown that TIMP-2-mediated inhibition of tumor growth is independent of matrix metalloproteinase-m...

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Autors principals: Bourboulia, Dimitra, Han, HuiYing, Jensen-Taubman, Sandra, Gavil, Noah, Isaac, Biju, Wei, Beiyang, Neckers, Len, Stetler-Stevenson, William G.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2013
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3702216/
https://ncbi.nlm.nih.gov/pubmed/23371049
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