Genomic imbalance of HMMR/RHAMM regulates the sensitivity and response of malignant peripheral nerve sheath tumour cells to aurora kinase inhibition

Malignant peripheral nerve sheath tumours (MPNST) are rare, hereditary cancers associated with neurofibromatosis type I. MPNSTs lack effective treatment options as they often resist chemotherapies and have high rates of disease recurrence. Aurora kinase A (AURKA) is an emerging target in cancer and...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mohan, Pooja, Castellsague, Joan, Jiang, Jihong, Allen, Kristi, Chen, Helen, Nemirovsky, Oksana, Spyra, Melanie, Hu, Kaiji, Kluwe, Lan, Pujana, Miguel Angel, Villanueva, Alberto, Mautner, Victor F., Keats, Jonathan J., Dunn, Sandra E., Lazaro, Conxi, Maxwell, Christopher A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2013
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3702209/
https://ncbi.nlm.nih.gov/pubmed/23328114
Tagiau: Ychwanegu Tag
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