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Dendritic cells prime a high avidity CTL response independent of the level of presented antigen

CTL that possess a high functional avidity are known to be optimal for the clearance of pathogens in vivo. We have shown that the amount of peptide encountered by a CD8(+) CTL determines its functional avidity. Notably, in these studies non-professional APC were utilized. However, it is mature DC th...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Kroger, Charles J., Amoah, Samuel, Alexander-Miller, Martha A.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2008
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3702053/
https://ncbi.nlm.nih.gov/pubmed/18424695
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