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Dendritic cells prime a high avidity CTL response independent of the level of presented antigen
CTL that possess a high functional avidity are known to be optimal for the clearance of pathogens in vivo. We have shown that the amount of peptide encountered by a CD8(+) CTL determines its functional avidity. Notably, in these studies non-professional APC were utilized. However, it is mature DC th...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3702053/ https://ncbi.nlm.nih.gov/pubmed/18424695 |
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