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Intrabodies as Neuroprotective Therapeutics

The process of misfolding of proteins that can trigger a pathogenic cascade leading to neurodegenerative diseases largely originates intracellularly. It is possible to harness the specificity and affinity of antibodies to counteract either protein misfolding itself, or the aberrant interactions and...

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Detalhes bibliográficos
Main Authors: Messer, Anne, Joshi, Shubhada N.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701772/
https://ncbi.nlm.nih.gov/pubmed/23649691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-013-0193-6
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