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Physico-chemical determinants of soluble intrabody expression in mammalian cell cytoplasm
Soluble antibody fragments are desirable not only as potential therapeutic and diagnostic agents for extracellular targets but also as ‘intrabodies’ for functional genomics, proteomics and gene therapy inside cells. However, antibody fragments are notoriously aggregation-prone when expressed intrace...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2865363/ https://ncbi.nlm.nih.gov/pubmed/20378699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzq022 |
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