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Antisense Oligonucleotides: Treating Neurodegeneration at the Level of RNA

Adequate therapies are lacking for Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, amyotrophic lateral sclerosis, and other neurodegenerative diseases. The ability to use antisense oligonucleotides (ASOs) to target disease-associated genes by means of RNA may offer a potent approach...

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Autori principali: DeVos, Sarah L., Miller, Timothy M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701770/
https://ncbi.nlm.nih.gov/pubmed/23686823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-013-0194-5
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