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Antisense Oligonucleotides: Treating Neurodegeneration at the Level of RNA

Adequate therapies are lacking for Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, amyotrophic lateral sclerosis, and other neurodegenerative diseases. The ability to use antisense oligonucleotides (ASOs) to target disease-associated genes by means of RNA may offer a potent approach...

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Detalhes bibliográficos
Main Authors: DeVos, Sarah L., Miller, Timothy M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701770/
https://ncbi.nlm.nih.gov/pubmed/23686823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-013-0194-5
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