Alu Elements in ANRIL Non-Coding RNA at Chromosome 9p21 Modulate Atherogenic Cell Functions through Trans-Regulation of Gene Networks

The chromosome 9p21 (Chr9p21) locus of coronary artery disease has been identified in the first surge of genome-wide association and is the strongest genetic factor of atherosclerosis known today. Chr9p21 encodes the long non-coding RNA (ncRNA) antisense non-coding RNA in the INK4 locus (ANRIL). ANR...

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Main Authors: Holdt, Lesca M., Hoffmann, Steve, Sass, Kristina, Langenberger, David, Scholz, Markus, Krohn, Knut, Finstermeier, Knut, Stahringer, Anika, Wilfert, Wolfgang, Beutner, Frank, Gielen, Stephan, Schuler, Gerhard, Gäbel, Gabor, Bergert, Hendrik, Bechmann, Ingo, Stadler, Peter F., Thiery, Joachim, Teupser, Daniel
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701717/
https://ncbi.nlm.nih.gov/pubmed/23861667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003588
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