Circular non-coding RNA ANRIL modulates ribosomal RNA maturation and atherosclerosis in humans

Circular RNAs (circRNAs) are broadly expressed in eukaryotic cells, but their molecular mechanism in human disease remains obscure. Here we show that circular antisense non-coding RNA in the INK4 locus (circANRIL), which is transcribed at a locus of atherosclerotic cardiovascular disease on chromoso...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Holdt, Lesca M., Stahringer, Anika, Sass, Kristina, Pichler, Garwin, Kulak, Nils A., Wilfert, Wolfgang, Kohlmaier, Alexander, Herbst, Andreas, Northoff, Bernd H., Nicolaou, Alexandros, Gäbel, Gabor, Beutner, Frank, Scholz, Markus, Thiery, Joachim, Musunuru, Kiran, Krohn, Knut, Mann, Matthias, Teupser, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4992165/
https://ncbi.nlm.nih.gov/pubmed/27539542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12429
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