Critical and Independent Role for SOCS3 in Either Myeloid or T Cells in Resistance to Mycobacterium tuberculosis

Suppressor of cytokine signalling 3 (SOCS3) negatively regulates STAT3 activation in response to several cytokines such as those in the gp130-containing IL-6 receptor family. Thus, SOCS3 may play a major role in immune responses to pathogens. In the present study, the role of SOCS3 in M. tuberculosi...

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Main Authors: Carow, Berit, Reuschl, Ann-Kathrin, Gavier-Widén, Dolores, Jenkins, Brendan J., Ernst, Matthias, Yoshimura, Akihiko, Chambers, Benedict J., Rottenberg, Martin E.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701707/
https://ncbi.nlm.nih.gov/pubmed/23853585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003442
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