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Predictors of Hepatitis B Cure Using Gene Therapy to Deliver DNA Cleavage Enzymes: A Mathematical Modeling Approach

Most chronic viral infections are managed with small molecule therapies that inhibit replication but are not curative because non-replicating viral forms can persist despite decades of suppressive treatment. There are therefore numerous strategies in development to eradicate all non-replicating viru...

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Detalhes bibliográficos
Main Authors: Schiffer, Joshua T., Swan, Dave A., Stone, Daniel, Jerome, Keith R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701691/
https://ncbi.nlm.nih.gov/pubmed/23861664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003131
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