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Predictors of hepatitis B cure using gene therapy to deliver DNA cleavage enzymes: a mathematical modeling approach.

Most chronic viral infections are managed with small molecule therapies that inhibit replication but are not curative because non-replicating viral forms can persist despite decades of suppressive treatment. There are therefore numerous strategies in development to eradicate all non-replicating viru...

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Detalhes bibliográficos
Main Authors: Joshua T Schiffer, Dave A Swan, Daniel Stone, Keith R Jerome
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2013-01-01
Colecção:PLoS Computational Biology
Acesso em linha:http://europepmc.org/articles/PMC3701691?pdf=render
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