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Cleavage of fragments containing DNA mismatches by enzymic and chemical probes.
We prepared synthetic 50-mer DNA duplexes, each containing four mismatched base-pairs in similar positions. We examined their cleavage by DNases I and II, micrococcal nuclease (MNase), methidiumpropyl-EDTA-Fe(II) [MPE-Fe(II)] and hydroxyl radicals. We find that single mismatches only produce subtle...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1223340/ https://ncbi.nlm.nih.gov/pubmed/12558499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021847 |
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