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Totipotent Embryonic Stem Cells Arise in Ground-State Culture Conditions
Embryonic stem cells (ESCs) are derived from mammalian embryos during the transition from totipotency, when individual blastomeres can make all lineages, to pluripotency, when they are competent to make only embryonic lineages. ESCs maintained with inhibitors of MEK and GSK3 (2i) are thought to repr...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3701323/ https://ncbi.nlm.nih.gov/pubmed/23746443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.04.034 |
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