Cold Exposure Promotes Atherosclerotic Plaque Growth and Instability via UCP1-Dependent Lipolysis

Molecular mechanisms underlying the cold-associated high cardiovascular risk remain unknown. Here, we show that the cold-triggered food-intake-independent lipolysis significantly increased plasma levels of small low-density lipoprotein (LDL) remnants, leading to accelerated development of atheroscle...

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Hauptverfasser: Dong, Mei, Yang, Xiaoyan, Lim, Sharon, Cao, Ziquan, Honek, Jennifer, Lu, Huixia, Zhang, Cheng, Seki, Takahiro, Hosaka, Kayoko, Wahlberg, Eric, Yang, Jianmin, Zhang, Lei, Länne, Toste, Sun, Baocun, Li, Xuri, Liu, Yizhi, Zhang, Yun, Cao, Yihai
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cell Press 2013
Schlagworte:
Short Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701322/
https://ncbi.nlm.nih.gov/pubmed/23823482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.06.003
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