Anti-VEGF– and anti-VEGF receptor–induced vascular alteration in mouse healthy tissues

Systemic therapy with anti-VEGF drugs such as bevacizumab is widely used for treatment of human patients with various solid tumors. However, systemic impacts of such drugs in host healthy vasculatures remain poorly understood. Here, we show that, in mice, systemic delivery of an anti-VEGF or an anti...

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Detalles Bibliográficos
Main Authors: Yang, Yunlong, Zhang, Yin, Cao, Ziquan, Ji, Hong, Yang, Xiaojuan, Iwamoto, Hideki, Wahlberg, Eric, Länne, Toste, Sun, Baocun, Cao, Yihai
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718173/
https://ncbi.nlm.nih.gov/pubmed/23818623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1301331110
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