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Reduced amyloidogenic processing of the amyloid β-protein precursor by the small-molecule Differentiation Inducing Factor-1

The detection of cell cycle proteins in Alzheimer’s disease (AD) brains may represent an early event leading to neurodegeneration. To identify cell cycle modifiers with anti-Aβ properties, we assessed the effect of Differentiation-Inducing Factor-1 (DIF-1), a unique, small-molecule from Dictyosteliu...

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Hlavní autoři: Myre, Michael A., Washicosky, Kevin, Moir, Robert D., Tesco, Giuseppina, Tanzi, Rudolph E., Wasco, Wilma
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701301/
https://ncbi.nlm.nih.gov/pubmed/19154786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2008.12.008
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