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Regulation of Lipid Signaling by Diacylglycerol Kinases during T Cell Development and Function

Diacylglycerol (DAG) and phosphatidic acid (PA) are bioactive lipids synthesized when the T cell receptor binds to a cognate peptide-MHC complex. DAG triggers signaling by recruiting Ras guanyl-releasing protein 1, PKCθ, and other effectors, whereas PA binds to effector molecules that include mechan...

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Bibliografski detalji
Glavni autori: Krishna, Sruti, Zhong, Xiao-Ping
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701226/
https://ncbi.nlm.nih.gov/pubmed/23847619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00178
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