Diacylglycerol Kinases in T Cell Tolerance and Effector Function

Diacylglycerol kinases (DGKs) are a family of enzymes that regulate the relative levels of diacylglycerol (DAG) and phosphatidic acid (PA) in cells by phosphorylating DAG to produce PA. Both DAG and PA are important second messengers cascading T cell receptor (TCR) signal by recruiting multiple effe...

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Bibliographic Details
Published in:Front Cell Dev Biol
Main Authors: Chen, Shelley S., Hu, Zhiming, Zhong, Xiao-Ping
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Cell and Developmental Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5103287/
https://ncbi.nlm.nih.gov/pubmed/27891502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2016.00130
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