LRRK2 in Parkinson’s Disease: Function in Cells and Neurodegeneration

Detailed characterization of LRRK2 function may provide insight into the molecular basis of neurodegeneration in Parkinson’s disease (PD) since mutations in LRRK2 cause a phenotype with strong overlap to typical late-onset disease and LRRK2 mutations are responsible for significant proportions of PD...

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Bibliographic Details
Main Authors: Webber, Philip J., West, Andrew B.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700730/
https://ncbi.nlm.nih.gov/pubmed/19804415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2009.07342.x
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