Pleiotrophin Suppression of Receptor Protein Tyrosine Phosphatase-β/ζ Maintains the Self-Renewal Competence of Fetal Human Oligodendrocyte Progenitor Cells

Oligodendrocyte progenitor cells (OPCs) persist in human white matter, yet the mechanisms by which they are maintained in an undifferentiated state are unknown. Human OPCs differentially express protein tyrosine phosphatase receptor β/ζ (PTPRZ1) and its inhibitory ligand, pleiotrophin, suggesting th...

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Hlavní autoři: McClain, Crystal R., Sim, Fraser J., Goldman, Steven A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700539/
https://ncbi.nlm.nih.gov/pubmed/23100427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1320-12.2012
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