The VP8* Domain of Neonatal Rotavirus Strain G10P[11] Binds to Type II Precursor Glycans

Naturally occurring bovine-human reassortant rotaviruses with a P[11] VP4 genotype exhibit a tropism for neonates. Interaction of the VP8* domain of the spike protein VP4 with sialic acid was thought to be the key mediator for rotavirus infectivity. However, recent studies have indicated a role for...

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Autors principals: Ramani, Sasirekha, Cortes-Penfield, Nicolas W., Hu, Liya, Crawford, Sue E., Czako, Rita, Smith, David F., Kang, Gagandeep, Ramig, Robert F., Le Pendu, Jacques, Prasad, B. V. Venkataram, Estes, Mary K.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
Matèries:
Virus-Cell Interactions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700318/
https://ncbi.nlm.nih.gov/pubmed/23616650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03518-12
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