Cell attachment protein VP8* of a human rotavirus specifically interacts with A-type histo-blood group antigen

As with many other viruses, the initial cell attachment of rotaviruses, major causative agent of infantile gastroenteritis, is mediated by interactions with specific cellular glycans(1–4). The distally located VP8* domain of the rotavirus spike protein VP4(5) mediates such interactions. The existing...

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Main Authors: Hu, Liya, Crawford, Sue E., Czako, Rita, Cortes-Penfield, Nicolas W, Smith, David F., Le Pendu, Jacques, Estes, Mary K., Venkataram Prasad, B. V.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350622/
https://ncbi.nlm.nih.gov/pubmed/22504179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10996
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